Radiesse®

RADIESSE® is the only evidence-based regenerative biostimulator[1] that stimulates new collagen and elastin with the versatility to also provide immediate volume and sharpened contours – for up to 12 months or longer in most patients.[1-6]

RADIESSE® is also the only evidence-based regenerative biostimulator[1] that reverses visible signs of aging and creates a more natural, youthful appearance. [2,7]

  • Improves skin foundation[8,9]
  • Meaningfully rebuilds skin[10]
  • Renews healthy-looking skin* tissue[1,11]
  • Provides immediate lift and sharpened contours[3]
  • Effectively regenerates skin over the long-term[3,4]

It can be used in a variety of indications and injection sites, offering versatility and flexibility to provide a wide range of personalized treatments.[5,6]

How does RADIESSE® work?

  • RADIESSE® is a unique, evidence-based treatment[1] that works to regenerate and restore the natural components of your skin to provide structure and support for more youthful looking, firmer skin.[1,7,8]
  • Acts directly to stimulate the creation of collagen, and key components of the skin’s structure to work against the signs of aging skin. [8,9]
  • Stimulates production of collagen and elastin, to provide support and structure to the skin and help smooth out wrinkles. [8,10]
  • Can reverse the visible signs of aging, providing long-term skin regeneration for up to 12 months or more. [1,6,11]

Benefits of using RADIESSE®

  • Up to 73.5% of patients saw improvements in décolleté wrinkles and lines lasting 16 weeks after treatment*. [12]
  • 76.1% of patients saw enhancements in skin quality lasting 16 weeks after treatment. †[12]
  • Doctors were satisfied with the décolleté treatment of 77% of patients at 16 weeks after treatment. [12]

called microspheres which are specifically designed to stimulate not only new collagen growth but also key components of the skin, helping to reverse the visible signs of aging [1,7,8].

Product Collection

Radiesse®
ΜΑΘΕΤΕ ΠΕΡΙΣΣΟΤΕΡΑ
radiesse plus
Radiesse®+
ΜΑΘΕΤΕ ΠΕΡΙΣΣΟΤΕΡΑ

*Improved at-rest appearance defined as a ≥1-point improvement on the Merz Aesthetics Scales Décolleté Wrinkles-At Rest assessed by the blinded live rater, analysed using a modified full analysis set with missing data replaced by a multiple imputation approach. 73.5% of patients showed improvement in appearance of at-rest décolleté wrinkles following two treatments. In the primary endpoint of the study,73.5% of patients pooled across treatment groups showed an improvement in the at-rest appearance of décolleté wrinkles 16 weeks after their last treatment.[12]

† Level of improvement in skin quality assessed according to iGAIS – Investigator Global Aesthetics Improvement Scale.[12]

1.Kim, J. Clin Cosmet Investig Dermatol. 2019;12:771–784
2.Yutskovskaya, Y, et al. J Drugs Dermatol. 2014;13(9):1047–1052
3.Durkin, A, et al. J Cosmet Dermatol. 2021;20(2):442–450
4.Baspeyras, M, et al. J Cosmet Dermatol. 2017;16(3):342–347
5.Pavicic, T. J Drugs Dermatol. 2013;12(9):996–1002.
6.RADIESSE®. Instructions for use. 2023.
7. Yutskovskaya, YA, et al. J Drugs Dermatol. 2020;19(4):405–411.
8. González, N, Goldberg, DJ. Dermatol Surg. 2019;45(4):547–551.
9. Wollina, U, Goldman, A. Dermatol Ther. 2020;33(6):e14183.
10. Courderot-Masuyer, C, et al. J Cosmet Dermatol. 2016;15(3):260–268.
11. Fabi, SG, et al. J Drugs Dermatol. 2021;20(5):534–537.
12. Merz Aesthetics®. Data on File. 2023.
13. Yutskovskaya, YA, Kogan,EA. J Drugs Dermatol. 2017;16(1):68–74.
14. Fisher, GJ, et al. Arch Dermatol. 2008;144(5):666–672.
15. Bass, LS, et al. Aesthet Surg J. 2010;30(2):235–238.
16.Van Loghem, J, et al. J Clin Aesthet Dermatol. 2015;8(1):38–49.
17. Draoui, O. The story of calcium hydroxylapatite. In: van Loghem, J, ed.Calcium Hydroxylapatite Soft Tissue Fillers. 2021.